INTRODUCTION
In America, more than 2000 people are diagnosed with this tumor each year, mostly one type of cancer suffered by children and adolescents, but few cases are found in adults.
Cancer around the bone itself consists of several types, namely osteosarcoma, Ewing's sarcoma, chondrosarcoma, malignant fibrous histiocytoma, fibrosarcoma, and Chordoma. Malignant fibrous histiocytoma (MFH) is a soft tissue sarcomas of the most frequently in older adulthood. There are several variants of the MFH, storiform-pleomorphic subtype, myxoid, inflammatory and giant cell. Infammatory and giant cell is a rare subtype. Most MFH tumors found in the soft tissue in the extremities and body. Giant cell MFH found in older patients.
CHAPTER I
DISCUSSION
I.1 Definition
Malignant fibrous Histiositoma (malignant fibrous histiocytoma) is a sarcoma that usually begins in the soft tissues. This condition usually appears as a large mass that is painful and can lead to fractures due to bone destruction by tumor spread.
Malignant fibrous histiocytoma was first introduced in 1961 by Kauffman and Stout. They describe as a tumor rich in histiocytes MFH with storiform growth pattern. In 1977, MFH is considered as soft tissue sarcomas of the most common of adult life.
I.2 Epidemiology
Malignant fibrous histiocytoma of soft tissue usually appears in patients is approximately 50 to 70 years although it can occur at any age. Malignant fibrous histiocytoma is very rare in people less than 20 years. More men than in women.
Malignant fibrous histiocytoma has a 44% recurrence rate and metastasis rate by 42%. Incidence of metastases to regional lymph nodes are found as much as 12%.
I.3 Histiologi
Histologist is divided into four subtypes:
A. Storiform-pleomorphic
Of these, storiform-pleomorphic is the most common type, accounting for up to 70% of cases, see Figure 1.
Figure 1: A histologic specimen shows fibrous histiocytoma classic storiform-pleomorphic malignant. Microscopically, the pattern shows fasikula short storiform spindle cells radiating from a central point which is mixed with giant neoplastic cells in the pleomorphic
2. Myxoid
Figure 2: Example of histological type myxoid MFH. So that the tumor will be marked as a variant of myxoid, myxoid tissue must explain at least half of the tumor
