Wilm's tumor (Nephroblastoma)
A. INTRODUCTION
Wilms tumor is the most malignancies and is the fifth most common renal tumor at the age of the children. These tumors most Appear at the age of three years and is rare after the age of 8 years. There are 250 cases of Wilms tumor ever reported. However, the preoperative diagnosis of Wilms' tumor in the adult is quite difficult. These tumors usually Appear as a solid renal mass with or without accompanied by hematuria. This solid mass may be accompanied by cystic part by focal necrosis and degeneration process. Sometimes radiological picture may resemble renal cysts hemorhagik. These tumors arise in one or two kidneys. (1) (7)
Diabdomen large masses, especially in children aged 1-5 years should arouse suspicion Wilm tumors. This neoplasm is aggressive and metastasizes to various organs, but to respond to combination therapy. Wilms tumor when Diagnosed and receive NAMAs therapy has a cure rate is quite high, reaching 90%. (1) (7)
The development of diagnostic imaging lately also play an important role in enhancing the efficacy and accuracy of the diagnosis of Wilms tumor and this is very important in designing the best combination therapy in children. (1) (7)
B. Epidemiology
Wilms Tumour incidence was 0.8 cases per 100,000 people. There are 500 new cases each year in the United States, and as much as 6% of it involves both kidneys. Risks incident to hit Wilm tumor is 1 in 10,000 births. Wilms tumor Occurs primarily in children under the age of 5 years. The incidence is highest between the ages of 1-3 years. It is estimated that these tumors in 7 Occurred between 1 million children in the United States and much of the African-American race. The ratio of female Patients and the male is almost balanced. (7)
